CURRICULUM VITAE

WRITING EXPERIENCE
Freelance writer for MSNBC.com, Science, The Scientist, University Week (University of Washington), Research Penn State, Renewable Energy World, Medicon Valley, Nordic Life Science Review, Natural Standard and others, 2008–present Creating feature articles on medicine, health and science

Contract writer and editor for Group Health Research Institute, Fred Hutchinson Cancer Research Center, Memorial Sloan-Kettering Cancer Center, Copenhagen University, the Danish Technical University, the Medical University of X'ian, China; Alk-Abelló, WHFreeman, McGraw-Hill, E-World Editing, Compuscript Limited, Write Science Right and others, 1992–present Writing, revising and formatting grant applications, journal articles and article summaries 

Writer and Developer, LEO Pharma Science Web site, 2006, 2010 Delivered draft Web pages focusing on basic and applied research at LEO Pharma

Writer and Developer, "Rediscovering Biology", Annenberg Media and Oregon Public Broadcasting, 2002–2003 Created case studies, activities and instructor guidelines for an online course aimed at high school biology teachers. Worked with producers, computer programmers, expert advisors and other writers

Primary author or editor for over 20 research articles, 1982–present Including a 2007 J. Biol. Chem. "Paper of the Week"

Member, American Medical Writers Association, Northwest Science Writers Association, and National Association of Science Writers

RESEARCH AND TEACHING EXPERIENCE
Honors Instructor, University of Washington, 2002–2010  

Research Scientist, Department of Biochemistry, University of Washington, 2002–2008 Investigated the effect of cell stress on transcriptional regulation in the laboratory of Dr. Ted Young

Visiting Scientist, Copenhagen University and Carlsberg Research Laboratories, Copenhagen, Denmark, 1996–2008 Collaborated with Dr. Jakob Winther on the cellular oxidation and reduction; Invited speaker at the Carlsberg Alumni Reunion, May 2010

Acting Assistant Professor and Research Scientist, University of Washington, 1999–2002 Taught biology and genetics while researching organelle biogenesis with Dr. Robin Wright

Instructor and Guest Scientist, Penn State University, 1993–1999 Taught biochemistry, genetics, cell biology, microbiology and general biology

Biology Instructor, Salt Lake Community College, 1992–1993 

Research Technician, Fred Hutchinson Cancer Research Center, 1982–1984 Studied the expression and intracellular localization of an oncogenic protein with Dr. Robert Eisenman

EDUCATION
 Ph.D Institute of Molecular Biology, University of Oregon 1991 Investigated mechanisms of intracellular protein sorting in yeast with Dr. Tom H. Stevens

M.S. Biochemistry, Molecular and Cell Biology, Cornell University  1987 Worked with Dr. Bik-Kwoon Tye on the characterization of a telomere-binding protein

B.A. Whitman College 1982 Major: Biology  Minor: Sociology

COMMUNITY SERVICE
Literacy Source 2009-present Assist in adult literacy classes

Seattle Pedestrian Advisory Board Secretary and Board Advisory writer, 2005–2009 Author of advisories to the Mayor and City Council on transportation and pedestrian issues 

On-Air Host and Board Operator for WPSU public radio station, University Park PA 1995–2000  Hosted National Public Radio news and information programs during normal operations and pledge drives;  Compiled and reported weather and local information for on-air broadcast

 

PUBLICATIONS

Video on freelance science writing and editing for ibiomagazine.org

Nielsen RW, Tachibana C, Hansen NE, Winther JR. Trisulfides in proteins. Antioxidants & Redox Signaling 2010. Epub ahead of print. [Abstract]

Kacherovsky N, Tachibana C, Amos E, Fox D III, Young ET. Promoter Binding by the Adr1 Transcriptional Activator May Be Regulated by Phosphorylation in the DNA-Binding Region. PLoS ONE 2008; 3(9):e3213. [Article]

Young ET, Tachibana C, Chang HW, Dombek KM, Arms EM, Biddick R. Artificial recruitment of mediator by the DNA-binding domain of Adr1 overcomes glucose repression of ADH2 expression. Mol Cell Biol 2008;28(8):2509–2516.  [Abstract]

Tachibana C, Biddick R, Law GL, Young ET. A poised initiation complex is activated by SNF1. J Biol Chem 2007;282(52):37308–37315. Chosen by JBiolChem as a featured "Paper of the Week", December 28, 2007. [Article]

Voronkova V, Kacherovsky N, Tachibana C, Yu D, Young ET.  Snf1-dependent and Snf1-independent pathways of constitutive ADH2 activation in Saccharomyces cerevisiae. Genetics 2006;172(4):2123–2138. [Abstract]

Loertscher J, Larson LL, Matson CK, Parrish ML, Felthauser, A, Sturm A, Tachibana C, Bard M, Wright R. Endoplasmic reticulum-associated degradation is required for cold adaptation and regulation of sterol biosynthesis in the yeast Saccharomyces cerevisiae. Eukaryot Cell 2006;5(4):712–722. [Abstract]

Tachibana C, Yoo, JY, Tagne J-B, Kacherovsky N, Lee TI, Young ET. Combined global localization analysis and transcriptome data identify genes that are directly coregulated by Adr1 and Cat8. Mol Cell Biol 200;25: 2138–2146. [Abstract]

Østergaard H, Tachibana C, Winther JR. Monitoring disulfide bond formation in the eukaryotic cytosol. J Cell Biol 2004;166(3):337–345. [Abstract]

Young ET, Dombek KM, Tachibana C, Ideker T. Multiple pathways are co-regulated by the protein kinase Snf1 and the transcription factors Adr1 and Cat8. J Biol Chem 2003;278:26146–16158. [Abstract]

Nørgaard P, Bruun A, Tachibana C, Winther JR. Gene regulation in response to protein disulfide isomerase deficiency. Yeast 2003;20:645–652. [Abstract]

Nørgaard P, Westphal V, Alsøe L, Tachibana C, Holst B, Winther JR. Functional differences in yeast protein disulfide isomerases. J Cell Biol 2001;152:1–11. [Abstract]

Holst B, Tachibana C, Winther JR. Active site mutations in yeast protein disulfide isomerase cause dithiothreitol sensitivity and a reduced rate of protein folding in the endoplasmic reticulum. J Cell Biol 1997; 138:1–10.  [Abstract]


Tachibana C, Stevens TH. The yeast EUG1 gene encodes an endoplasmic reticulum protein that is functionally related to protein disulfide isomerase. Mol Cell Biol 1992;12:4601–4611. [Abstract]

Berman J, Tachibana CY, Tye B-K. Identification of a telomere-binding activity from yeast. Proc Natl Acad Sci 1986;83:3713–3717. [Abstract]

Eisenman RN, Tachibana CY, Abrams HD, Hann SR. v-myc and c-myc-encoded proteins are associated with the nuclear matrix. Mol Cell Biol 1985;5:114–126.  [Abstract]

SEMINARS
March 2011 ibiomagazine "Freelance science writing and editing"

September 2010 Fourth Military Medical University at X'ian China Invited speaker, "How to publish and present: the basics" and "How to publish and present: advanced tips"

May 2010 Carlsberg Research Center, Denmark Invited speaker, Carlsberg Alumni Reunion "Can't drink beer, can't say brød (but Carlsberg let me visit anyway)"

March 2004 Fred Hutchinson Cancer Research Center, USA Seattle Area Yeast Group seminar "Adr1 and Cat8, fighting for global change…in gene expression"

November 2001 University of Washington, USA Genome Sciences Research Reports "ER redox and membrane biogenesis"

May 1999 Carlsberg Research Center, Denmark Departmental Seminar "Protein folding and the unfolded protein response in yeast"

August 1992 Penn State University, USA Biochemistry Department seminar "Characterization of a yeast protein disulfide isomerase"

COURSES TAUGHT
University of Washington 2000–2010

HON ART/SCI 396     Honors Discussion for Introductory Biology
BIOL201                   Introductory Biology
GENET351                Human Genetics for non-majors
GENET371                Introductory Genetics
GENET490                Undergraduate Seminar
BIOL 499                  Undergraduate Research

Penn State University 1993–2000
BMB101, 121            Introductory Biochemisty, Applied Biochemistry
GEN222                    Introductory Genetics

MICRB106                Elementary Microbiology
BiSci 001                  Biology for non-majors
BiSci004                   Human Biology for non-majors
BMB 251                  Molecular and Cell Biology
BMB 411                  Microbiology and Biochemistry Literature
MICRB435                Medical Virology
BIOL230                  Cell Biology

Salt Lake Community College 1992–1993
Introductory Biology, Microbiology, Cell Biology

Cornell University 1984–1985
(graduate teaching assistant)
Advanced Biochemistry Laboratory
Auto-tutorial Biochemistry